Hepatitis C virus (HCV) infections affect more than 170 million people worldwide.Most of these individuals are chronically infected, but some clear the infection rapidly.Host factors seem to play a key role in HCV clearance, among them the human leukocyte antigen (HLA) class I molecules.Certain HLA molecules, e.g.B*27 and B*57, are associated with
A Microring Resonator Based Negative Permeability Metamaterial Sensor
Metamaterials are artificial multifunctional materials that acquire their material properties from their structure, rather than inheriting them directly from the materials they are composed of, and they may provide novel tools to significantly enhance the sensitivity and resolution of sensors.In this paper, we derive the dispersion relation of a cy
Averaged Soft Actor-Critic for Deep Reinforcement Learning
With the advent of the era of artificial intelligence, deep reinforcement learning (DRL) has achieved unprecedented success in high-dimensional and large-scale artificial intelligence tasks.However, the insecurity and instability of the DRL algorithm have an important impact on its performance.The Soft Actor-Critic (SAC) algorithm uses advanced fun
Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males
Zancong Shen, Colin Rowlings, Brad Kerr, Vijay Hingorani, Kimberly Manhard, Barry Quart, Li-Tain Yeh, Chris Storgard Ardea Biosciences, Inc.(a member of the AstraZeneca group), San Diego, CA, USA Abstract: Lesinurad is a selective uric acid reabsorption inhibitor under investigation for the treatment of gout.Single and multiple ascending dose studi
Peran Financial Distress Risk Sebagai Variabel Moderasi Pada Pengaruh Financial Leverage Terhadap Financial Performance
Financial distress risk merupakan isu penting dalam memilih struktur modal dan dapat memengaruhi hubungan antara leverage dengan kinerja keuangan.Perusahaan perlu Pier memperhatikan financial distress karena dapat berdampak buruk bahkan menimbulkan terjadinya kebangkrutan.Pada penelitian ini, peneliti menguji peran financial distress risk sebagai v